{"id":4546,"date":"2024-11-12T16:54:40","date_gmt":"2024-11-12T08:54:40","guid":{"rendered":"http:\/\/baijianyy.cn\/?p=4546"},"modified":"2024-12-12T19:25:08","modified_gmt":"2024-12-12T11:25:08","slug":"%e7%bb%a5%e5%8c%96%e5%b8%82%e6%9c%9b%e5%a5%8e%e5%8e%bf-%e6%b7%ae%e5%ae%89%e6%9c%89%e9%98%bb%e6%96%ad%e8%8d%af%e4%b9%88%ef%bc%9f%e4%b8%ba%e4%bd%95%e8%89%be%e6%bb%8b%e5%a6%82%e6%ad%a4%e9%9a%be%e6%b2%bb","status":"publish","type":"post","link":"http:\/\/baijianyy.cn\/?p=4546","title":{"rendered":"\u7ee5\u5316\u5e02\u671b\u594e\u53bf \u6dee\u5b89\u6709\u963b\u65ad\u836f\u4e48\uff1f\u4e3a\u4f55\u827e\u6ecb\u5982\u6b64\u96be\u6cbb\u7597\uff1f"},"content":{"rendered":"<p>\u827e\u6ecb\u75c5\u963b\u65ad\u836f\u54ea\u91cc\u8d2d\u4e70\uff0c\u827e\u6ecb\u75c5\u963b\u65ad\u836f\u4ef7\u683c\uff0c\u827e\u6ecb\u75c5\u963b\u65ad\u836f\u54c1\u9500\u552e\u673a\u6784\uff1f<br 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src=\"http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/11\/1-1.gif\" alt=\"\" width=\"300\" height=\"300\" \/><\/p>\n<p>\u6dee\u5b89\u6709\u963b\u65ad\u836f\u4e48\uff1f\u6b64\u95ee\u9898\u8bf7\u626b\u4e0a\u9762\u7684\u4e8c\u7ef4\u7801\u5173\u6ce8\u4e92\u8054\u7f51\u533b\u9662\uff0c\u4e3a\u60a8\u89e3\u7b54\uff01<\/p>\n<p>\u81ea\u613f\u54a8\u8be2\u68c0\u6d4b\u673a\u6784\uff1a\u671b\u594e\u53bf\u75be\u75c5\u63a7\u5236\u4e2d\u5fc3<\/p>\n<p>\u5730\u5740\uff1a\u671b\u594e\u53bf\u5e7f\u573a\u8857\u67ab\u6797\u798f\u90b8\u897f\u5357\u4fa7\u7ea6<span lang=\"EN-US\">100<\/span>\u7c73<\/p>\n<p>\u5168\u7403\u8fd14000\u4e07\u4eba\u611f\u67d3\u827e\u6ecb\u75c5\u6bd2<\/p>\n<section><strong>2021\u5e74\uff0c\u670965\u4e07\u4eba\u6b7b\u4e8e\u827e\u6ecb\u75c5\u6bd2\u76f8\u5173\u539f\u56e0\uff0c150\u4e07\u4eba\u611f\u67d3\u827e\u6ecb\u75c5\u6bd2\u3002\u622a\u81f32021\u5e74\u5e95\uff0c\u5168\u7403\u4f30\u8ba1\u67093840\u4e07\u827e\u6ecb\u75c5\u6bd2\u611f\u67d3\u8005<sup>[2]<\/sup>\u3002<\/strong><\/p>\n<\/section>\n<section><\/section>\n<section>\u7136\u800c\uff0c\u5728\u201c\u6297\u827e\u201d\u56db\u5341\u5e74\u95f4\uff0c\u53ea\u6709\u6781\u4e2a\u522b\u7684\u75c5\u4f8b\u51fa\u73b0\u201c\u75ca\u6108\u201d\u7684\u8ff9\u8c61\u3002\u6bcf\u51fa\u73b0\u4e00\u4f4d\u8fd9\u6837\u7684\u60a3\u8005\uff0c\u90fd\u4f1a\u8ba9\u5927\u4f17\u6b22\u6b23\u9f13\u821e\u3002<\/p>\n<\/section>\n<section><\/section>\n<section>\u4e3a\u4f55\u827e\u6ecb\u75c5\u5982\u6b64\u96be\u653b\u514b\uff0c\u6211\u4eec\u79bb\u6cbb\u6108\u827e\u6ecb\u75c5\u8fd8\u6709\u591a\u8fdc\uff1f\u4eca\u5929\u4e00\u8d77\u6765\u4e86\u89e3\u8fd9\u4e00\u201c\u4e16\u7eaa\u96be\u9898\u201d\u3002<\/p>\n<p>\u4e3a\u4f55\u827e\u6ecb\u75c5\u5982\u6b64\u96be\u6cbb?<\/p>\n<section><\/section>\n<section><strong>\u827e\u6ecb\u75c5\u4e4b\u6240\u4ee5\u96be\u6cbb\u6108\uff0c\u5f88\u5927\u7684\u539f\u56e0\u5728\u4e8e\u827e\u6ecb\u75c5\u6bd2\u5177\u6709\u5f88\u5f3a\u7684\u201c\u9690\u8eab\u201d\u80fd\u529b\u3002<\/strong><\/p>\n<\/section>\n<section><\/section>\n<section>\u5f53\u827e\u6ecb\u75c5\u6bd2\u8fdb\u5165\u4eba\u4f53\u540e\uff0c\u5b83\u4f1a\u5c06\u81ea\u5df1\u6574\u5408\u5230\u51e0\u79cd\u7ec6\u80de\u7c7b\u578b\u7684\u5bbf\u4e3b\u57fa\u56e0\u7ec4\u4e2d<sup>[3]<\/sup>\u3002\u5728\u90a3\u91cc\uff0c\u5b83\u4eec\u53ef\u4ee5\u4e0d\u65ad\u590d\u5236\uff0c\u5236\u9020\u66f4\u591a\u7684\u201c\u5206\u8eab\u201d\uff0c\u6301\u7eed\u653b\u51fb\u66f4\u591a\u7684\u7ec6\u80de\u3002<\/p>\n<\/section>\n<section><\/section>\n<section>\u867d\u7136\uff0c\u4f7f\u7528\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u836f\u7269\u53ef\u4ee5\u963b\u65ad\u8fd9\u4e00\u8fc7\u7a0b\uff0c\u4f46\u201c\u72e1\u733e\u201d\u7684\u75c5\u6bd2\u7adf\u7136\u4f1a\u201c\u6f5c\u4f0f\u201d\u8d77\u6765\uff0c\u8fdb\u5165\u4f11\u7720\u72b6\u6001\uff0c\u4ece\u800c\u53ef\u4ee5\u8eb2\u8fc7\u4eba\u4f53\u514d\u75ab\u7cfb\u7edf\u548c\u836f\u7269\u3002\u4e00\u65e6\u505c\u6b62\u6cbb\u7597\uff0c\u75c5\u6bd2\u53c8\u4f1a\u5377\u571f\u91cd\u6765\u3002<\/p>\n<\/section>\n<section><\/section>\n<section>\u56e0\u6b64\uff0c\u60f3\u7cbe\u51c6\u5b9a\u4f4d\u3001\u6709\u6548\u6253\u51fb\u3001\u5f7b\u5e95\u6839\u9664\u827e\u6ecb\u75c5\u6bd2\uff0c\u662f\u4e00\u4ef6\u5341\u5206\u6709\u96be\u5ea6\u7684\u4e8b\u60c5\u3002<\/p>\n<section>\u5176\u6b21\uff0c\u827e\u6ecb\u75c5\u6bd2\u5177\u6709\u5f88\u5f3a\u7684\u7a81\u53d8\u80fd\u529b\u3002<\/p>\n<\/section>\n<section><\/section>\n<section>\u827e\u6ecb\u75c5\u6bd2\u5728\u4eba\u4f53\u5185\u6301\u7eed\u8fdb\u884c\u7684\uff0c\u5e76\u4e0d\u662f\u5355\u7eaf\u7684\u201c\u590d\u5236\u201d\u4e0e\u201c\u7c98\u8d34\u201d\u3002<\/p>\n<\/section>\n<section><\/section>\n<section>\u9006\u8f6c\u5f55\u3001\u91cd\u7ec4\u3001\u5c06\u75c5\u6bd2DNA\u5e8f\u5217\u8f6c\u5f55\u4e3aRNA\u4ece\u800c\u5168\u8eab\u4f20\u64ad\u2026\u2026\u5728\u8fd9\u4e00\u6301\u7eed\u800c\u9891\u7e41\u8fdb\u884c\u7684\u8fc7\u7a0b\u4e2d\uff0c\u75c5\u6bd2\u5f88\u5bb9\u6613\u51fa\u9519\uff0c\u4ece\u800c\u5bfc\u81f4\u201c\u7a81\u53d8\u201d\u3002<\/p>\n<\/section>\n<section><\/section>\n<section>\u6bcf\u4e00\u79cd\u7a81\u53d8\u90fd\u4f1a\u8ba9\u514d\u75ab\u7cfb\u7edf\u66f4\u96be\u4ee5\u8bc6\u522b\uff0c\u8ba9\u6cbb\u7597\u836f\u7269\u4e00\u7b79\u83ab\u5c55\u3002\u79d1\u5b66\u5bb6\u8ba4\u4e3a\uff0c\u8fd9\u79cd\u9891\u7e41\u7684\u7a81\u53d8\u662f\u514d\u75ab\u7cfb\u7edf\u65e0\u6cd5\u6839\u9664\u75c5\u6bd2\u7684\u4e3b\u8981\u539f\u56e0\u4e4b\u4e00\u3002<\/p>\n<\/section>\n<section><\/section>\n<section>\u56e0\u6b64\uff0c\u6cbb\u7597\u827e\u6ecb\u75c5\u611f\u67d3\u8005\uff0c\u5f80\u5f80\u5f88\u96be\u53ea\u7528\u4e00\u79cd\u836f\u7269\uff0c\u800c\u662f\u901a\u5e38\u4f7f\u7528\u9e21\u5c3e\u9152\u7597\u6cd5\uff08\u4f7f\u7528\u4e24\u79cd\u53ca\u4ee5\u4e0a\u836f\u7269\u8054\u5408\u6cbb\u7597\uff09\u3002<\/p>\n<section>\u201c\u6297\u827e\u201d\u7684\u9053\u8def\u5e76\u4e0d\u662f\u4e00\u5e06\u98ce\u987a\u3002\u8fc7\u53bb40\u5e74\uff0c\u5168\u4e16\u754c\u7684\u79d1\u5b66\u5bb6\u4eec\u5728\u7ecf\u5386\u4e86\u8bb8\u591a\u5931\u8d25\u4e0e\u56f0\u987f\u4e4b\u540e\uff0c\u4e5f\u53d6\u5f97\u4e86\u957f\u8db3\u7684\u8fdb\u6b65\uff0c\u83b7\u5f97\u4e86\u4e00\u4e9b\u5353\u6709\u6548\u679c\u7684\u8fdb\u5c55\u3002<\/p>\n<\/section>\n<section><\/section>\n<section><strong>1.\u00a0\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u836f\u7269\u6cbb\u7597<\/strong><\/p>\n<\/section>\n<section><\/section>\n<section>1996\u5e74\uff0c\u534e\u88d4\u79d1\u5b66\u5bb6\u4f55\u5927\u4e00\u63d0\u51fa\u4e86\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u8054\u5408\u7597\u6cd5\uff0c\u4fd7\u79f0\u201c\u9e21\u5c3e\u9152\u7597\u6cd5\u201d\u3002\u8fd9\u4e00\u91cc\u7a0b\u7891\u5f0f\u7684\u6cbb\u7597\u65b9\u6848\u4f7f\u7528\u4e24\u79cd\u4ee5\u4e0a\u7684\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u7ec4\u5408\uff0c\u5c55\u73b0\u51fa\u4e86\u5f3a\u5927\u7684\u6291\u5236\u827e\u6ecb\u75c5\u6bd2\u4f5c\u7528\u3002<\/p>\n<\/section>\n<section><\/section>\n<section>\u9488\u5bf9\u827e\u6ecb\u75c5\u7684\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u836f\u7269\u4e3b\u8981\u5206\u4e3a6\u5927\u7c7b\uff0c\u5206\u522b\u4e3a<sup>[5]<\/sup>\uff1a<\/p>\n<\/section>\n<section><\/section>\n<section>\n<ul class=\"list-paddingleft-1\">\n<li>\u6838\u82f7\u7c7b\u9006\u8f6c\u5f55\u9176\u6291\u5236\u5242\uff08NRTI\uff09\uff1a\u9f50\u591a\u592b\u5b9a\uff0c\u62c9\u7c73\u592b\u5b9a<\/li>\n<li>\u975e\u6838\u82f7\u7c7b\u9006\u8f6c\u5f55\u9176\u6291\u5236\u5242\uff08NNRTI\uff09\uff1a\u5948\u97e6\u62c9\u5e73\uff0c\u4f9d\u975e\u97e6\u4f26\uff0c\u5229\u5339\u97e6\u6797<\/li>\n<li>\u86cb\u767d\u9176\u6291\u5236\u5242\uff08PI\uff09\uff1a\u6d1b\u5339\u90a3\u97e6\/\u5229\u6258\u90a3\u97e6<\/li>\n<li>\u6574\u5408\u9176\u94fe\u8f6c\u79fb\u6291\u5236\u5242\uff08INSTI\uff09\uff1a\u591a\u66ff\u62c9\u97e6\uff0c\u62c9\u66ff\u62c9\u97e6<\/li>\n<li>\u878d\u5408\u9176\u6291\u5236\u5242\uff08FI\uff09\uff1a\u827e\u535a\u97e6\u6cf0<\/li>\n<li>CCR5\u6291\u5236\u5242<\/li>\n<\/ul>\n<\/section>\n<section><\/section>\n<section>\u4e16\u754c\u536b\u751f\u7ec4\u7ec7\u5728\u6700\u65b0\u7684\u6307\u5357\u4e2d\uff0c\u63a8\u8350\u4ee5\u591a\u66ff\u62c9\u97e6\uff08\u5c5e\u4e8e\u6574\u5408\u9176\u94fe\u8f6c\u79fb\u6291\u5236\u5242\uff09\u8054\u5408\u4e00\u79cd\u6838\u82f7\u7c7b\u9006\u8f6c\u5f55\u9176\u6291\u5236\u5242\uff08NRTI\uff09\u4f5c\u4e3a\u4e00\u7ebf\u6cbb\u7597\u65b9\u6848<sup>[4]<\/sup>\u3002<\/p>\n<section><\/section>\n<p>\u6211\u56fd\u63a8\u83502\u79cd\u6838\u82f7\u7c7b\u9006\u8f6c\u5f55\u9176\u6291\u5236\u5242\uff08NRTI\uff09\u836f\u7269\u8054\u5408\u7b2c\u4e09\u7c7b\u836f\u7269\u6cbb\u7597\u3002\u7b2c\u4e09\u7c7b\u836f\u7269\u53ef\u4ee5\u662f\u975e\u6838\u82f7\u7c7b\u9006\u8f6c\u5f55\u9176\u6291\u5236\u5242\uff08NNRTI\uff09\u6216\u662f\u589e\u5f3a\u578b\u86cb\u767d\u9176\u6291\u5236\u5242\uff08PI\uff09<sup>[5]<\/sup>\u3002<\/p>\n<\/section>\n<section><\/section>\n<section><strong>\u4e0d\u8fc7\uff0c\u65e0\u8bba\u662f\u5e72\u7ec6\u80de\u79fb\u690d\uff0c\u8fd8\u662f\u57fa\u56e0\u7f16\u8f91\u6280\u672f\uff0c\u76ee\u524d\u90fd\u8fd8\u9762\u4e34\u7740\u8bf8\u591a\u6280\u672f\u6311\u6218\u548c\u4f26\u7406\u98ce\u9669\u3002\u5b83\u4eec\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u4e5f\u8fd8\u9700\u8fdb\u4e00\u6b65\u8bc1\u5b9e\u3002<\/strong><\/p>\n<\/section>\n<section><\/section>\n<section><span 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