{"id":3387,"date":"2024-03-31T09:24:32","date_gmt":"2024-03-31T01:24:32","guid":{"rendered":"http:\/\/baijianyy.cn\/?p=3387"},"modified":"2024-03-31T09:24:32","modified_gmt":"2024-03-31T01:24:32","slug":"%e9%82%b5%e9%98%b3%e5%b8%82%e5%a4%a7%e7%a5%a5%e5%8c%ba%e9%98%bb%e6%96%ad%e8%89%be%e6%bb%8b%e7%97%85%e6%af%92%e7%9a%84%e8%8d%af%e6%9c%89%e5%93%aa%e4%ba%9b%ef%bc%9f","status":"publish","type":"post","link":"http:\/\/baijianyy.cn\/?p=3387","title":{"rendered":"\u90b5\u9633\u5e02\u5927\u7965\u533a\u963b\u65ad\u827e\u6ecb\u75c5\u6bd2\u7684\u836f\u6709\u54ea\u4e9b\uff1f"},"content":{"rendered":"<p>\u827e\u6ecb\u75c5\u963b\u65ad\u836f\u54ea\u91cc\u8d2d\u4e70\uff0c\u827e\u6ecb\u75c5\u963b\u65ad\u836f\u4ef7\u683c\uff0c\u827e\u6ecb\u75c5\u963b\u65ad\u836f\u54c1\u9500\u552e\u673a\u6784\uff1f<br \/>\npep\u963b\u65ad\u836f\u3001prep\u963b\u65ad\u836f\u5168\u56fd\u4e24\u5c0f\u65f6\u6025\u9001\uff0c\u836f\u5e97\u76f4\u53d1\uff0c\u4e13\u4eba\u4e13\u9001<br \/>\n\u827e\u6ecb\u75c5HIV\u66b4\u9732\u524d\u540e\u963b\u65ad\u9884\u9632\u7528\u836f\uff0c\u8bf7\u626b\u7801\u6dfb\u52a0\u533b\u9662\u5ba2\u670d\uff0c\u5168\u56fd\u5404\u57ce\u5e02\u6700\u5feb2\u5c0f\u65f6\u5de6\u53f3\u9001\u8fbe\u3002<br \/>\n\u9ad8\u5371\u884c\u4e3a\u540e\u591a\u4e45\u68c0\u6d4b\uff1f\u9ad8\u5371\u6027\u884c\u4e3a\u4e00\u6b21\u8981\u5403\u963b\u65ad\u836f\u5417\uff1f\u53d1\u751f\u9ad8\u5371\u6027\u884c\u4e3a\u540e\u600e\u4e48\u529e\uff1f\u9ad8\u5371\u884c\u4e3a\u591a\u5c11\u5929\u540e\u53ef\u4ee5\u5f7b\u5e95\u6392\u9664\uff1f\u7b49\u7b49\u95ee\u9898\uff0c\u53ef\u4ee5\u5728\u4e92\u8054\u7f51\u533b\u9662\u514d\u8d39\u54a8\u8be2\u4e13\u4e1a\u611f\u67d3\u79d1\u533b\u5e08\u3002<img decoding=\"async\" loading=\"lazy\" class=\"aligncenter size-full wp-image-3252\" src=\"http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/mmexport1702183130138-1-1-1.gif\" alt=\"\" width=\"300\" height=\"300\" 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\u6e56\u5357\u7701\u90b5\u9633\u5e02\u5b9d\u5e86\u897f\u8def162\u53f7\u5927\u7965\u533a\u4e8c\u7eba\u7ea7\u804c\u5de5\u533b\u9662\u5185<\/p>\n<p>\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u836f\u7269\u7528\u4e8e\u6cbb\u7597\u827e\u6ecb\u75c5\u6bd2\u611f\u67d3\u3002\u5b83\u4eec\u901a\u8fc7\u963b\u6b62\u75c5\u6bd2\u751f\u547d\u5468\u671f\u7684\u67d0\u4e2a\u9636\u6bb5\u6765\u5de5\u4f5c\uff0c\u5e76\u901a\u8fc7\u8fd9\u6837\u505a\u6765\u9632\u6b62\u75c5\u6bd2\u590d\u5236\u3002\u8fd9\u4e9b\u836f\u7269\u4e3b\u8981\u6839\u636e\u5b83\u4eec\u6291\u5236\u7684\u751f\u547d\u5468\u671f\u9636\u6bb5\u5206\u4e3a\u516d\u4e2a\u4e0d\u540c\u7684\u7c7b\u522b\u3002<\/p>\n<p>\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u7597\u6cd5\u6b63\u5728\u8fc5\u901f\u53d8\u5316\uff0c\u8f83\u65b0\u7684\u836f\u7269\u5177\u6709\u66f4\u5c11\u7684\u526f\u4f5c\u7528\uff0c\u66f4\u9ad8\u7684\u8010\u53d7\u6027\u548c\u66f4\u4f4e\u7684\u8010\u836f\u6027\u98ce\u9669\u3002\u8fc7\u53bb\uff0c\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u7597\u6cd5\u88ab\u63cf\u8ff0\u4e3a\u4e09\u79cd\u836f\u7269\u7684&#8221;\u9e21\u5c3e\u9152&#8221;\u3002\u4eca\u5929\uff0c\u968f\u7740\u836f\u4ee3\u52a8\u529b\u5b66\u7684\u6539\u5584\u548c\u836f\u7269\u534a\u8870\u671f\u7684\u5ef6\u957f\uff0c\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u6cbb\u7597\u53ef\u80fd\u53ea\u6d89\u53ca\u4e24\u79cd\u5171\u540c\u914d\u5236\u7684\u836f\u7269\u3002<\/p>\n<p>\u76ee\u524d\u56fd\u9645\u4e0a\u5171\u6709\u516d\u5927\u7c7b30\u591a\u79cd\u836f\u7269\uff0c\u5206\u522b\u4e3a\u6838\u82f7\u7c7b\u53cd\u8f6c\u5f55\u9176\u6291\u5236\u5242\uff08NRTIs\uff09\u3001\u975e\u6838\u82f7\u7c7b\u53cd\u8f6c\u5f55\u9176\u6291\u5236\u5242\uff08NNRTIs\uff09\u3001\u86cb\u767d\u9176\u6291\u5236\u5242\uff08PIs\uff09\u3001\u6574\u5408\u9176\u6291\u5236\u5242\uff08INSTIs\uff09\u3001\u878d\u5408\u6291\u5236\u5242\uff08FIs\uff09\u53caCCR5\u6291\u5236\u5242\u3002\u56fd\u5185\u7684\u6297\u53cd\u8f6c\u5f55\u75c5\u6bd2\u6cbb\u7597\u836f\u7269\u6709NRTIs\u3001NNRTIs\u3001PIs\u3001INSTIs\u4ee5\u53caFIs\u4e94\u5927\u7c7b\uff08\u5305\u62ec\u590d\u5408\u5236\u5242\uff09\u3002<\/p>\n<p>&nbsp;<\/p>\n<p><strong>01. \u6838\u82f7\u9006\u8f6c\u5f55\u9176\u6291\u5236\u5242<\/strong><\/p>\n<p>\u4e3a\u4e86\u4f7fHIV\u80fd\u591f\u590d\u5236\uff0cHIV\u4f7f\u7528\u4e00\u79cd\u79f0\u4e3a\u9006\u8f6c\u5f55\u9176\u7684\u9176\u5c06\u5176\u75c5\u6bd2RNA\u7ffb\u8bd1\u6210\u53cc\u94feDNA\uff0c\u7136\u540e\u5c06\u5176\u6574\u5408\u5230\u5bbf\u4e3b\u7ec6\u80de\u7684\u7ec6\u80de\u6838\u4e2d\u4ee5&#8221;\u52ab\u6301&#8221;\u5176\u9057\u4f20\u673a\u5236\u3002\u901a\u8fc7\u8fd9\u6837\u505a\uff0cHIV\u53ef\u4ee5\u5f00\u59cb\u4ea7\u751f\u81ea\u8eab\u7684\u591a\u4e2a\u526f\u672c\u3002<\/p>\n<p>\u6838\u82f7\u7c7b\u9006\u8f6c\u5f55\u9176\u6291\u5236\u5242\uff08NRTIs\uff09\u963b\u65ad\u9006\u8f6c\u5f55\u9176\u7684\u4f5c\u7528\uff0c\u4ece\u800c\u963b\u6b62\u75c5\u6bd2\u7684\u590d\u5236\u3002<img decoding=\"async\" loading=\"lazy\" class=\"aligncenter size-full wp-image-3388\" src=\"http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/640-7-1.png\" alt=\"\" width=\"919\" height=\"621\" srcset=\"http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/640-7-1.png 919w, http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/640-7-1-768x519.png 768w\" sizes=\"(max-width: 919px) 100vw, 919px\" \/><\/p>\n<p><strong>02. \u975e\u6838\u82f7\u7c7b\u9006\u8f6c\u5f55\u9176\u6291\u5236\u5242<\/strong><\/p>\n<p>\u975e\u6838\u82f7\u7c7b\u9006\u8f6c\u5f55\u9176\u6291\u5236\u5242\uff08NNRTIs\uff09\u4e5f\u963b\u65ad\u9006\u8f6c\u5f55\u9176\uff0c\u4f46\u65b9\u5f0f\u4e0d\u540c\u3002NNRTIs\u4e0d\u50cfNRTI\u90a3\u6837\u9644\u7740\u5728\u75c5\u6bd2DNA\u4e0a\uff0c\u800c\u662f\u76f4\u63a5\u4e0e\u9176\u7ed3\u5408\uff0c\u963b\u65ad\u5176\u4f5c\u7528\u3002<img decoding=\"async\" loading=\"lazy\" class=\"aligncenter size-full wp-image-3389\" src=\"http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/640-8-1.jpg\" alt=\"\" width=\"906\" height=\"487\" srcset=\"http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/640-8-1.jpg 906w, http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/640-8-1-768x413.jpg 768w\" sizes=\"(max-width: 906px) 100vw, 906px\" \/><\/p>\n<section><strong>03. \u86cb\u767d\u9176\u6291\u5236\u5242<\/strong><\/section>\n<section>\u86cb\u767d\u9176\u6291\u5236\u5242\uff08PI\uff09\u901a\u8fc7\u963b\u65ad\u4e00\u79cd\u79f0\u4e3a\u86cb\u767d\u9176\u7684\u9176\u8d77\u4f5c\u7528\u3002\u4e00\u65e6HIV\u63a5\u7ba1\u4e86\u5bbf\u4e3b\u7ec6\u80de\u7684\u9057\u4f20\u673a\u5236\uff0c\u5b83\u5c31\u4f1a\u4ea7\u751f\u957f\u94fe\u86cb\u767d\u8d28\uff0c\u8fd9\u4e9b\u86cb\u767d\u8d28\u5fc5\u987b\u88ab\u5207\u5272\u6210\u66f4\u5c0f\u7684\u7247\u6bb5\uff08\u901a\u8fc7\u86cb\u767d\u9176\uff09\u624d\u80fd\u7ec4\u88c5\u6210\u65b0\u7684\u75c5\u6bd2\u9897\u7c92\u3002\u901a\u8fc7\u4e0e\u86cb\u767d\u9176\u7ed3\u5408\uff0c\u957f\u94fe\u86cb\u767d\u4e0d\u80fd\u88ab\u5207\u5272\uff0c\u5e76\u4e14\u4e0d\u80fd\u4ea7\u751f\u65b0\u7684\u75c5\u6bd2\u9897\u7c92\u3002<img decoding=\"async\" loading=\"lazy\" class=\"aligncenter size-full wp-image-3390\" src=\"http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/640-8-1.png\" alt=\"\" width=\"912\" height=\"261\" srcset=\"http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/640-8-1.png 912w, http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/640-8-1-768x220.png 768w\" sizes=\"(max-width: 912px) 100vw, 912px\" \/><\/section>\n<section>\n<section><strong>04. \u6574\u5408\u9176\u6291\u5236\u5242<\/strong><\/section>\n<section>\u6574\u5408\u9176\u6291\u5236\u5242\u901a\u8fc7\u963b\u65adHIV\u7684DNA\u63ba\u5165\u5bbf\u4e3b\u7ec6\u80de\u7684DNA\u6765\u8d77\u4f5c\u7528\uff0c\u8fd9\u4e00\u8fc7\u7a0b\u79f0\u4e3a\u6574\u5408\u3002\u5b83\u4eec\u901a\u8fc7\u6291\u5236\u4e00\u79cd\u79f0\u4e3a\u6574\u5408\u9176\u7684\u75c5\u6bd2\u9176\u6765\u5b9e\u73b0\u8fd9\u4e00\u70b9\u3002<img decoding=\"async\" loading=\"lazy\" class=\"aligncenter size-full wp-image-3391\" src=\"http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/640-9-1.png\" alt=\"\" width=\"921\" height=\"277\" srcset=\"http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/640-9-1.png 921w, http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/640-9-1-768x231.png 768w\" sizes=\"(max-width: 921px) 100vw, 921px\" \/><\/section>\n<section>\n<section><strong>05. \u590d\u65b9\u5236\u5242<\/strong><\/section>\n<section>\u56fa\u5b9a\u5242\u91cf\u8054\u5408\u7528\u836f\u53ef\u51cf\u8f7b\u827e\u6ecb\u75c5\u6bd2\u611f\u67d3\u8005\u5728\u63a5\u53d7\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u6cbb\u7597\u65f6\u53ef\u80fd\u9762\u4e34\u7684\u6bcf\u65e5\u836f\u7247\u8d1f\u62c5\u3002<\/section>\n<section>\n<table cellspacing=\"0\" cellpadding=\"0\">\n<tbody>\n<tr>\n<td width=\"69\" height=\"19\"><strong>\u836f\u7269\u540d\u79f0<\/strong><\/td>\n<td width=\"53\"><strong>\u7f29\u5199<\/strong><\/td>\n<td width=\"57\"><strong>\u7c7b\u522b<\/strong><\/td>\n<td width=\"224\"><strong>\u7528\u6cd5\u7528\u91cf<\/strong><\/td>\n<td width=\"75\"><strong>\u4e3b\u8981\u4e0d\u826f\u53cd\u5e94<\/strong><\/td>\n<td width=\"57\"><strong>\u5546\u54c1\u540d<\/strong><\/td>\n<\/tr>\n<tr>\n<td width=\"69\" height=\"37\">\u591a\u66ff\u62c9\u97e6\/\u62c9\u7c73\u592b\u5b9a<\/td>\n<td width=\"53\">DTG\/<br \/>\n3TC<\/td>\n<td width=\"57\">INSTIs+\u00a0 NRTIs<\/td>\n<td width=\"224\">1\u7247\/\u6b21\uff0c1 \u00a0\u6b21\/d<\/td>\n<td width=\"75\">\u89c1DTG\u548c3TC<\/td>\n<td width=\"57\">\u591a\u4f1f\u6258<\/td>\n<\/tr>\n<tr>\n<td width=\"69\" height=\"75\">\u591a\u66ff\u62c9\u97e6\/\u963f\u5df4\u5361\u97e6\/\u62c9\u7c73\u592b\u5b9a<\/td>\n<td width=\"53\">DTG\/<br \/>\nABC\/<br \/>\n3TC<\/td>\n<td width=\"57\">INSTIs+\u00a0 NRTIs<\/td>\n<td width=\"224\">\u6210\u4eba\u548c12\u5c81\u53ca\u4ee5\u4e0a\u4e14\u4f53\u91cd\u226540 \u00a0kg\u7684\u9752\u5c11\u5e74\uff0c1\u7247\/ \u6b21\uff0c1 \u6b21\/d\uff08\u6bcf\u7247\u542b\u91cf\uff1aDTG 50 mg\/ABC 600 mg<br \/>\n\/3TC 300 mg\uff09<\/td>\n<td width=\"75\">\u89c1ABC\u3001DTG\u548c3TC<\/td>\n<td width=\"48\">\u7ee5\u7f8e\u51ef<\/td>\n<\/tr>\n<tr>\n<td width=\"69\" height=\"93\">\u827e\u7ef4\u96f7\u97e6\/\u8003\u6bd4\u53f8\u4ed6\/\u6069\u66f2\u4ed6\u6ee8\/\u4e19\u915a\u66ff\u8bfa\u798f\u97e6<\/td>\n<td width=\"53\">EVG\/c\/FTC\/<br \/>\nTAF<\/td>\n<td width=\"57\">INSTIs+\u00a0 NRTIs<\/td>\n<td width=\"224\">\u6210\u4eba\u548c\u5e74\u9f84\u4e3a12\u5c81\u53ca\u4ee5\u4e0a\u4e14\u4f53\u91cd\u2265 \u00a035 kg\u7684\u9752\u5c11\u5e74\uff0c1\u7247\/\u6b21\uff0c1 \u6b21\/d\uff08\u6bcf\u7247\u542b\u91cf\uff1aEVG\/c\/FTC\/TAF150 mg\/150 mg\/200 mg\/10 mg\uff09\uff0c\u968f\u9910\u670d\u7528<\/td>\n<td width=\"75\">1\uff09\u8179\u6cfb\uff1b2\uff09\u6076\u5fc3\uff1b3\uff09\u5934\u75db<\/td>\n<td width=\"48\">\u6377\u6276\u5eb7<\/td>\n<\/tr>\n<tr>\n<td width=\"69\" height=\"75\">\u6bd4\u514b\u66ff\u62c9\u97e6\/\u6069\u66f2\u4ed6\u6ee8\/\u4e19\u915a\u66ff\u8bfa\u798f\u97e6<\/td>\n<td width=\"53\">BIC\/<br \/>\nFTC\/<br \/>\nTAF<\/td>\n<td width=\"57\">INSTIs+\u00a0 NRTIs<\/td>\n<td width=\"224\">\u6210\u4eba\uff0c1\u7247\/\u6b21\uff0c1\u6b21\/d\uff08\u6bcf\u7247\u542b\u91cf\uff1aBIC\/FTC\/TAF \u00a050mg\/200 mg\/25 mg\uff09<\/td>\n<td width=\"75\">1\uff09\u5934\u75db\uff1b2\uff09\u8179\u6cfb\uff1b3\uff09\u6076\u5fc3<\/td>\n<td width=\"48\">\u5fc5\u59a5\u7ef4<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/section>\n<\/section>\n<\/section>\n","protected":false},"excerpt":{"rendered":"\u827e\u6ecb\u75c5\u963b\u65ad\u836f\u54ea\u91cc\u8d2d\u4e70\uff0c\u827e\u6ecb\u75c5\u963b\u65ad\u836f\u4ef7\u683c\uff0c\u827e\u6ecb\u75c5\u963b\u65ad\u836f\u54c1\u9500\u552e\u673a\u6784\uff1f","protected":false},"author":4,"featured_media":3390,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5,3,4,57],"tags":[58,61,60,79],"_links":{"self":[{"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/posts\/3387"}],"collection":[{"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3387"}],"version-history":[{"count":1,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/posts\/3387\/revisions"}],"predecessor-version":[{"id":3392,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/posts\/3387\/revisions\/3392"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/media\/3390"}],"wp:attachment":[{"href":"http:\/\/baijianyy.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3387"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3387"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3387"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}