{"id":3022,"date":"2024-03-24T15:49:56","date_gmt":"2024-03-24T07:49:56","guid":{"rendered":"http:\/\/baijianyy.cn\/?p=3022"},"modified":"2024-03-24T15:49:56","modified_gmt":"2024-03-24T07:49:56","slug":"%e6%9d%be%e5%8e%9f%e5%b8%82%e9%95%bf%e5%b2%ad%e5%8e%bf30%e5%b0%8f%e6%97%b6%e9%98%bb%e6%96%ad%e8%8d%af%e6%88%90%e5%8a%9f%e7%8e%87%e5%a4%9a%e5%b0%91%ef%bc%9fhiv%e6%84%9f%e6%9f%93%e8%80%85%ef%bc%8c","status":"publish","type":"post","link":"http:\/\/baijianyy.cn\/?p=3022","title":{"rendered":"\u677e\u539f\u5e02\u957f\u5cad\u53bf30\u5c0f\u65f6\u963b\u65ad\u836f\u6210\u529f\u7387\u591a\u5c11\uff1fHIV\u611f\u67d3\u8005\uff0c\u7edd\u5bf9\u4e0d\u5e94\u8be5\u5408\u5e76\u4f7f\u7528\u7684\u836f\u7269\u6709\u54ea\u4e9b\uff1f"},"content":{"rendered":"<p>\u827e\u6ecb\u75c5<a href=\"http:\/\/baijianyy.cn\/?tag=%e9%98%bb%e6%96%ad%e8%8d%af\" title=\"\u6d4f\u89c8\u5173\u4e8e\u201c\u963b\u65ad\u836f\u201d\u7684\u6587\u7ae0\" target=\"_blank\" class=\"tag_link\">\u963b\u65ad\u836f<\/a>\u54ea\u91cc\u8d2d\u4e70\uff0c\u827e\u6ecb\u75c5\u963b\u65ad\u836f\u4ef7\u683c\uff0c\u827e\u6ecb\u75c5\u963b\u65ad\u836f\u54c1\u9500\u552e\u673a\u6784\uff1f<br \/>\npep\u963b\u65ad\u836f\u3001prep\u963b\u65ad\u836f\u5168\u56fd\u4e24\u5c0f\u65f6\u6025\u9001\uff0c\u836f\u5e97\u76f4\u53d1\uff0c\u4e13\u4eba\u4e13\u9001<br \/>\n\u827e\u6ecb\u75c5HIV\u66b4\u9732\u524d\u540e\u963b\u65ad\u9884\u9632\u7528\u836f\uff0c\u8bf7\u626b\u7801\u6dfb\u52a0\u533b\u9662\u5ba2\u670d\uff0c\u5168\u56fd\u5404\u57ce\u5e02\u6700\u5feb2\u5c0f\u65f6\u5de6\u53f3\u9001\u8fbe\u3002<br \/>\n\u9ad8\u5371\u884c\u4e3a\u540e\u591a\u4e45\u68c0\u6d4b\uff1f<a href=\"http:\/\/baijianyy.cn\/?tag=%e9%ab%98%e5%8d%b1%e6%80%a7%e8%a1%8c%e4%b8%ba\" title=\"\u6d4f\u89c8\u5173\u4e8e\u201c\u9ad8\u5371\u6027\u884c\u4e3a\u201d\u7684\u6587\u7ae0\" target=\"_blank\" class=\"tag_link\">\u9ad8\u5371\u6027\u884c\u4e3a<\/a>\u4e00\u6b21\u8981\u5403\u963b\u65ad\u836f\u5417\uff1f\u53d1\u751f\u9ad8\u5371\u6027\u884c\u4e3a\u540e\u600e\u4e48\u529e\uff1f\u9ad8\u5371\u884c\u4e3a\u591a\u5c11\u5929\u540e\u53ef\u4ee5\u5f7b\u5e95\u6392\u9664\uff1f\u7b49\u7b49\u95ee\u9898\uff0c\u53ef\u4ee5\u5728\u4e92\u8054\u7f51\u533b\u9662\u514d\u8d39\u54a8\u8be2\u4e13\u4e1a\u611f\u67d3\u79d1\u533b\u5e08\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"size-full wp-image-2910 aligncenter\" src=\"http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/mmexport1702183130138-2.gif\" alt=\"\" width=\"300\" height=\"300\" \/><\/p>\n<p>30\u5c0f\u65f6\u963b\u65ad\u836f\u6210\u529f\u7387\u591a\u5c11\uff1f\u6b64\u95ee\u9898\u8bf7\u626b\u4e0a\u9762\u7684\u4e8c\u7ef4\u7801\u5173\u6ce8\u4e92\u8054\u7f51\u533b\u9662\uff0c\u4e3a\u60a8\u89e3\u7b54\uff01<\/p>\n<p>\u81ea\u613f\u54a8\u8be2\u68c0\u6d4b\u673a\u6784\uff1a\u957f\u5cad\u53bf\u75be\u75c5\u9884\u9632\u63a7\u5236\u4e2d\u5fc3<\/p>\n<p>\u5730\u5740\uff1a\u677e\u539f\u5e02\u957f\u5cad\u53bf\u957f\u5cad\u9547\u5cad\u57ce\u4e1c\u8def<span lang=\"EN-US\">1468<\/span>\u53f7<\/p>\n<section>\n<section>\u670d\u7528HIV\u836f\u7269\u7684\u60a3\u8005\uff0c\u7ecf\u5e38\u62c5\u5fc3\u8ddf\u522b\u7684\u836f\u7269\u4e00\u8d77\u5403\uff0c\u4f1a\u4e0d\u4f1a\u6709\u76f8\u4e92\u5e72\u6270\uff0c\u533b\u5b66\u4e0a\u79f0\u4e3a<strong>\u836f\u7269\u76f8\u4e92\u4f5c\u7528<\/strong>\u3002\u7684\u786e\u6709\u5f88\u591a\u836f\u7269\u4f1a\u5b58\u5728\u5e72\u6270\uff0c\u4f46\u662f\u4e5f\u4e0d\u7528\u7279\u522b\u62c5\u5fc3\u3002\u6211\u4eec\u628a\u6700\u9700\u8981\u6ce8\u610f\u7684\u836f\u7269\u76f8\u4e92\u4f5c\u7528\u505a\u4e00\u4e2a\u6574\u7406\u3002<\/p>\n<\/section>\n<\/section>\n<section>\n<section>\u4e00\u822c\u7684\u611f\u5192\u836f\u3001\u6297\u8fc7\u654f\u836f\u3001\u6b62\u75bc\u836f\u3001\u6b62\u5410\u6216\u8005\u6b62\u6cfb\u836f\u3001\u6297\u751f\u7d20\u7b49\u5e38\u7528\u836f\u7269\uff0c\u90fd\u548cHIV\u836f\u7269\u6ca1\u6709\u76f8\u4e92\u4f5c\u7528\u3002<strong>\u9700\u8981\u6ce8\u610f\u7684\u662f\u80c3\u836f\u3001\u5b89\u7720\u836f\u3001\u964d\u80c6\u56fa\u9187\u836f\u3001\u9ad8\u8840\u538b\u836f\u3001\u907f\u5b55\u836f\u548c\u58ee\u9633\u836f\u7b49\u7b49\u3002<\/strong>\u81f3\u4e8e<strong>\u4e2d\u836f<\/strong>\uff08\u5305\u62ec\u6210\u836f\u3001\u8349\u836f\u3001\u51b2\u5242\u3001\u8721\u4e38\u7b49\uff09\u3001<strong>\u8865\u54c1\u3001\u5065\u5eb7\u4fdd\u5065\u98df\u54c1\uff0c\u4f1a\u4e0d\u4f1a\u8ddfHIV\u836f\u7269\u6709\u76f8\u4e92\u4f5c\u7528<\/strong>\uff0c\u5f88\u591a\u90fd\u6ca1\u6709\u88ab\u7814\u7a76\u8fc7\uff0c\u60f3\u8981\u670d\u7528\u7684\u60a3\u8005\u5c31\u81ea\u884c\u627f\u62c5\u98ce\u9669\uff0c\u6211\u4eec\u5e76<strong>\u4e0d\u9f13\u52b1\u548cHIV\u836f\u7269\u4e00\u8d77\u670d\u7528<\/strong>\u3002\u5982\u679c\u9700\u8981\u670d\u7528\uff0c\u670d\u7528\u524d\u9700\u5145\u5206\u54a8\u8be2\u533b\u751f\u6216\u836f\u5e08\uff0c\u5e76\u9694\u5f00\u8db3\u591f\u7684\u65f6\u95f4\uff08\u81f3\u5c114\u4e2a\u5c0f\u65f6\uff09\uff0c\u90e8\u5206\u836f\u7269\u8fd8\u9700\u77e5\u9053\u9910\u524d\u6216\u9910\u540e\u670d\u7528\u8981\u6c42\u3002<\/p>\n<section>\n<section><strong>1 <\/strong><strong>\u7edd\u5bf9\u4e0d\u5e94\u8be5\u5408\u5e76\u4f7f\u7528\u7684\u836f\u7269<\/strong><\/p>\n<\/section>\n<\/section>\n<section>\n<section>HIV\u836f\u7269\u5355\u4e2d\uff0c\u86cb\u767d\u9176\u6291\u5236\u5242\uff08PI\uff09\u548c\u5c5e\u4e8e\u975e\u6838\u82f7\u9178\u53cd\u8f6c\u5f55\u9176\uff08NNRTI\uff09\u7684\u5229\u5339\u97e6\u6797\uff08RPV\uff09\uff0c\u56e0\u4e3a\u900f\u8fc7\u809d\u810f\u7279\u6b8a\u9176\u7cfb\u7edf\u4ee3\u8c22\uff0c\u4f1a\u8ddf\u540c\u6837\u5229\u7528\u8fd9\u4e2a\u7cfb\u7edf\u4ee3\u8c22\u7684\u836f\u7269\u53d1\u751f\u76f8\u4e92\u4f5c\u7528\uff0c\u5f7c\u6b64\u5e72\u6270\u3002<\/p>\n<\/section>\n<\/section>\n<section>\n<section><strong>\u6709\u4e9b\u836f\u7269\u76f8\u4e92\u4f5c\u7528\u7684\u7ed3\u679c\uff0c\u662f\u8ba9\u836f\u7269\u6d53\u5ea6\u5347\u9ad8\uff0c\u751a\u81f3\u4ea7\u751f\u6bd2\u6027\u3002<\/strong>\u4f8b\u5982\u67d0\u4e9b\u5c06\u80c6\u56fa\u9187\u836f\u7269\u548cPI\u5408\u5e76\u7528\uff0c\u4f1a\u8ba9\u964d\u80c6\u56fa\u9187\u836f\u7269\u6d53\u5ea6\u5927\u589e\uff0c\u4ea7\u751f\u81f4\u547d\u7684\u6a2a\u7eb9\u808c\u6eb6\u89e3\u526f\u4f5c\u7528\uff0c\u4e25\u91cd\u65f6\u9700\u8981\u8840\u6db2\u900f\u6790\uff0c\u56e0\u6b64<strong>\u7edd\u5bf9\u4e0d\u80fd\u8ddfPI\u5408\u5e76\u7528<\/strong>\u3002<\/p>\n<\/section>\n<\/section>\n<section>\n<section><strong>\u6709\u4e9b\u836f\u7269\u76f8\u4e92\u4f5c\u7528\u7684\u7ed3\u679c\uff0c\u5219\u662f\u8ba9\u836f\u7269\u6d53\u5ea6\u5927\u5e45\u964d\u4f4e\uff0c\u4e27\u5931\u6cbb\u7597\u6548\u679c\u3002<\/strong>\u4f8b\u5982\u6297\u7ed3\u6838\u836f\u5229\u798f\u5e73\uff0c\u8ddfPI\u6216\u8005\u5229\u5339\u97e6\u6797\u5408\u7528\u65f6\uff0c\u4f1a\u8ba9PI\u6216\u5229\u5339\u97e6\u6797\u7684\u836f\u7269\u6d53\u5ea6\u964d\u4f4e70%~90%\uff0c\u5bfc\u81f4HIV\u6cbb\u7597\u5931\u8d25\uff0c\u56e0\u6b64<strong>\u5229\u798f\u5e73\u662f\u7edd\u5bf9\u4e0d\u80fd\u548cPI\u6216\u5229\u5339\u97e6\u6797\u5408\u7528\u7684<\/strong>\u3002<\/p>\n<\/section>\n<\/section>\n<section>\n<section>\u8fd9\u4e9b\u4e25\u91cd\u7684<strong>\u836f\u7269\u4ea4\u4e92\u4f5c\u7528<\/strong>\uff0c\u4e0d\u8bba\u8ba9\u6bd2\u6027\u589e\u52a0\u6216\u8ba9\u836f\u6548\u4e27\u5931\uff0c\u90fd\u4f1a\u88ab\u5217\u4e3a\u533b\u5b66\u4e0a\u7684\u201c<strong>\u4f7f\u7528\u7981\u5fcc<\/strong>\u201d\uff0c\u4efb\u4f55\u60c5\u51b5\u4e0b\u90fd\u4e0d\u5e94\u8be5\u5408\u5e76\u4f7f\u7528\u3002<\/p>\n<section>\n<section><strong>2\u00a0 <\/strong><strong>\u9ebb\u70e6\u7684\u80c3\u836f\uff1a\u5f71\u54cd\u80c3\u80a0\u9053\u5438\u6536\u67d0\u7c7b\u836f\u7269<\/strong><\/p>\n<\/section>\n<\/section>\n<section>\n<section><strong>\u80c3\u836f\u53ef\u80fd\u8ba9\u67d0\u4e9bHIV\u836f\u7269\u4ece\u80c3\u80a0\u9053\u5438\u6536\u51cf\u5f31\uff0c\u5bfc\u81f4\u836f\u7269\u6d53\u5ea6\u4e0d\u8db3\u3002<\/strong>\u539f\u7406\u4e3b\u8981\u6709\u4e24\u7c7b\uff1a<\/p>\n<\/section>\n<\/section>\n<section>\n<section><strong>(1)\u51cf\u5c11\u80c3\u9178\u5206\u6ccc<\/strong><\/p>\n<\/section>\n<\/section>\n<section>\n<section>\u80c3\u80a0\u836f\u51cf\u5c11\u80c3\u9178\u5206\u6ccc\u3001\u5f71\u54cd\u9700\u8981\u80c3\u9178\u624d\u80fd\u5438\u6536\u7684\u836f\u7269\u3002\u4f8b\u5982ATV\u3001RPV\u7b49\u9700\u8981\u80c3\u9178\u624d\u80fd\u5438\u6536\u7684HIV\uff0c\u5c31\u4e0d\u5b9c\u5408\u5e76\u80c3\u836f\u4f7f\u7528\u3002<\/p>\n<\/section>\n<\/section>\n<section>\n<section>\u901a\u5e38\u5e38\u89c1\u836f\u7269\u4e3a\u4e24\u7c7b\uff1a<strong>\u7b2c\u4e00\u7c7bH2\u53d7\u4f53\u62ee\u6297\u5242<\/strong>\uff0c\u4f8b\u5982\u6cd5\u83ab\u66ff\u4e01\u3001\u897f\u54aa\u66ff\u4e01\u3001\u96f7\u7c73\u66ff\u4e01\uff1b<strong>\u7b2c\u4e8c\u7c7b\u662f\u6c22\u79bb\u5b50\u5e2e\u6d66\u6291\u5236\u5242<\/strong>\uff0c\u4f8b\u5982\u96f7\u8d1d\u62c9\u5511\u3001\u827e\u53f8\u5965\u7f8e\u62c9\u5511\u3001\u5170\u7d22\u62c9\u5511\u3001\u6cee\u6258\u62c9\u5511\u3002<\/p>\n<\/section>\n<\/section>\n<section><\/section>\n<section>\n<section><strong>(2)\u94dd\u9541\u9644\u7740<\/strong><\/p>\n<\/section>\n<\/section>\n<section>\n<section>\u80c3\u836f\u5e38\u542b\u6709\u94dd\u3001\u9541\u7b49\u4e8c\u4ef7\u6216\u4e09\u4ef7\u9633\u79bb\u5b50\u3001\u4f1a\u9644\u7740\u5728RAL\u3001DTG\u8fd9\u4e2aINSTI\u836f\u7269\uff0c\u5bfc\u81f4\u80c3\u80a0\u9053\u5438\u6536\u51cf\u5f31\u3002<\/p>\n<section>\n<section><strong>3<\/strong><\/p>\n<\/section>\n<\/section>\n<section>\n<section>\n<section>\n<section>\n<section><strong>\u5371\u9669\u7ec4\u5408\uff1aHIV\u836f\u7269\u4e0e\u65b0\u578b\u6bd2\u54c1\u7684\u76f8\u4e92\u4f5c\u7528<\/strong><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<section>\n<section>\u65b0\u578b\u6bd2\u54c1\u5982\u6447\u5934\u4e38\u3001K\u4ed6\u547d\u3001\u5b89\u975e\u4ed6\u547d\u7b49\uff0c\u6709\u53ef\u80fd\u4e0e\u67d0\u4e9bHIV\u836f\u7269\u53d1\u751f\u76f8\u4e92\u4f5c\u7528\uff0c\u5bfc\u81f4<strong>\u8840\u6db2\u4e2d\u836f\u7269\u6d53\u5ea6\u660e\u663e\u6539\u53d8<\/strong>\uff0c\u5f15\u53d1\u65b0\u578b\u6bd2\u54c1\u836f\u7269\u8fc7\u91cf\u7684\u4e25\u91cd\u4e0d\u826f\u53cd\u5e94\u3002<\/p>\n<\/section>\n<\/section>\n<section>\n<section>\u6700\u5e38\u89c1\u7684\u6447\u5934\u4e38\uff08\u5b89\u975e\u4ed6\u547d\uff0c\u53c8\u79f0\u51b0\u6bd2\uff0c\u6216\u5176\u884d\u751f\u7269\uff09\uff0c\u56e0\u4e3a\u4e0ePI\u5171\u7528\u76f8\u540c\u7684\u809d\u810f\u4ee3\u8c22\u7cfb\u7edf\uff0c\u5728\u670d\u7528PI\uff08LPV\/r\u3001ATV\u3001DRV\uff09\u65f6\uff0c<strong>\u6447\u5934\u4e38\u836f\u6548\u4f1a\u589e\u52a0\u5e76\u5ef6\u957f\uff0c\u4e25\u91cd\u4f1a\u53d1\u751f\u731d\u6b7b\u75c7\u72b6<\/strong>\u3002<\/p>\n<\/section>\n<\/section>\n<section>\n<section>K\u4ed6\u547d\uff08\u6c2f\u80fa\u916e\uff09\u5728\u4e0eRitonavir\u53ef\u4ee5\u53d1\u751f<strong>\u4e25\u91cd\u7684\u809d\u810f\u635f\u5bb3<\/strong>\u3002<\/p>\n<\/section>\n<\/section>\n<section>\n<section>\u5b89\u975e\u4ed6\u547d\u5728\u4e8ePI\u5408\u7528\u65f6\u4f1a\u8ba9\u5b89\u975e\u4ed6\u547d\u7684\u836f\u6548\u589e\u52a02~3\u500d\uff0c<strong>\u5f15\u8d77\u4e2d\u6bd2\uff0c\u5bfc\u81f4\u731d\u6b7b<\/strong>\u3002RUSH\uff08\u809b\u95e8\u677e\u5f1b\u5242\uff09\u4e0e\u5b89\u975e\u4ed6\u547d\u5408\u7528\uff0c\u8fd8\u4f1a\u5ef6\u7f13\u5b89\u975e\u4ed6\u547d\u5728\u809d\u810f\u4e2d\u7684\u4ee3\u8c22\u5bfc\u81f4\u4e2d\u6bd2\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"alignnone size-full wp-image-3023\" src=\"http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/u12481598412757435636fm253fmtautoapp138fJPEG.webp.jpg\" alt=\"\" width=\"500\" height=\"682\" \/><\/p>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n<\/section>\n","protected":false},"excerpt":{"rendered":"\u827e\u6ecb\u75c5\u963b\u65ad\u836f\u54ea\u91cc\u8d2d\u4e70\uff0c\u827e\u6ecb\u75c5\u963b\u65ad\u836f\u4ef7\u683c\uff0c\u827e\u6ecb\u75c5\u963b\u65ad\u836f\u54c1\u9500\u552e\u673a\u6784\uff1f","protected":false},"author":2,"featured_media":3023,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[5,4,57],"tags":[52,394,50,81],"_links":{"self":[{"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/posts\/3022"}],"collection":[{"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3022"}],"version-history":[{"count":1,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/posts\/3022\/revisions"}],"predecessor-version":[{"id":3024,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/posts\/3022\/revisions\/3024"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/media\/3023"}],"wp:attachment":[{"href":"http:\/\/baijianyy.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3022"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3022"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3022"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}