{"id":2468,"date":"2024-03-01T16:47:38","date_gmt":"2024-03-01T08:47:38","guid":{"rendered":"http:\/\/baijianyy.cn\/?p=2468"},"modified":"2024-12-12T21:13:44","modified_gmt":"2024-12-12T13:13:44","slug":"%e4%b8%8a%e9%a5%b6%e5%b8%82%e5%a9%ba%e6%ba%90%e5%8e%bf%e9%98%bb%e6%96%ad%e8%8d%af%e4%b8%ba%e4%bb%80%e4%b9%88%e8%a6%81%e5%90%8328%e5%a4%a9%ef%bc%9f%e7%be%8e%e5%9b%bd%e5%9b%b4%e4%ba%a7%e6%9c%9fhiv","status":"publish","type":"post","link":"http:\/\/baijianyy.cn\/?p=2468","title":{"rendered":"\u4e0a\u9976\u5e02\u5a7a\u6e90\u53bf\u963b\u65ad\u836f\u4e3a\u4ec0\u4e48\u8981\u540328\u5929\uff1f\u7f8e\u56fd\u56f4\u4ea7\u671fHIV\u4e34\u5e8a\u6307\u53572024\u5e74\u91cd\u78c5\u66f4\u65b0\uff1a\u5fc5\u59a5\u7ef4\u53ef\u4ee5\u7528\u4e8e\u5b55\u5987\u4e86"},"content":{"rendered":"<p>\u827e\u6ecb\u75c5<a class=\"tag_link\" title=\"\u6d4f\u89c8\u5173\u4e8e\u201c\u963b\u65ad\u836f\u201d\u7684\u6587\u7ae0\" href=\"http:\/\/baijianyy.cn\/?tag=%e9%98%bb%e6%96%ad%e8%8d%af\" target=\"_blank\" rel=\"noopener\">\u963b\u65ad\u836f<\/a>\u54ea\u91cc\u8d2d\u4e70\uff0c\u827e\u6ecb\u75c5<a class=\"tag_link\" title=\"\u6d4f\u89c8\u5173\u4e8e\u201c\u963b\u65ad\u836f\u201d\u7684\u6587\u7ae0\" href=\"http:\/\/baijianyy.cn\/?tag=%e9%98%bb%e6%96%ad%e8%8d%af\" target=\"_blank\" rel=\"noopener\">\u963b\u65ad\u836f<\/a>\u4ef7\u683c\uff0c\u827e\u6ecb\u75c5<a class=\"tag_link\" title=\"\u6d4f\u89c8\u5173\u4e8e\u201c\u963b\u65ad\u836f\u201d\u7684\u6587\u7ae0\" href=\"http:\/\/baijianyy.cn\/?tag=%e9%98%bb%e6%96%ad%e8%8d%af\" target=\"_blank\" rel=\"noopener\">\u963b\u65ad\u836f<\/a>\u54c1\u9500\u552e\u673a\u6784\uff1f<br \/>\npep<a class=\"tag_link\" title=\"\u6d4f\u89c8\u5173\u4e8e\u201c\u963b\u65ad\u836f\u201d\u7684\u6587\u7ae0\" href=\"http:\/\/baijianyy.cn\/?tag=%e9%98%bb%e6%96%ad%e8%8d%af\" target=\"_blank\" rel=\"noopener\">\u963b\u65ad\u836f<\/a>\u3001prep<a class=\"tag_link\" title=\"\u6d4f\u89c8\u5173\u4e8e\u201c\u963b\u65ad\u836f\u201d\u7684\u6587\u7ae0\" href=\"http:\/\/baijianyy.cn\/?tag=%e9%98%bb%e6%96%ad%e8%8d%af\" target=\"_blank\" rel=\"noopener\">\u963b\u65ad\u836f<\/a>\u5168\u56fd\u4e24\u5c0f\u65f6\u6025\u9001\uff0c\u836f\u5e97\u76f4\u53d1\uff0c\u4e13\u4eba\u4e13\u9001<\/p>\n<p><a class=\"tag_link\" title=\"\u6d4f\u89c8\u5173\u4e8e\u201c\u827e\u6ecb\u75c5\u201d\u7684\u6587\u7ae0\" href=\"http:\/\/baijianyy.cn\/?tag=%e8%89%be%e6%bb%8b%e7%97%85\" target=\"_blank\" rel=\"noopener\">\u827e\u6ecb\u75c5<\/a>HIV\u66b4\u9732\u524d\u540e\u963b\u65ad\u9884\u9632\u7528\u836f\uff0c\u8bf7\u626b\u7801\u6dfb\u52a0\u533b\u9662\u5ba2\u670d\uff0c<strong>\u5168\u56fd\u5404\u57ce\u5e02<\/strong>\u6700\u5feb2\u5c0f\u65f6\u5de6\u53f3\u9001\u8fbe\u3002<\/p>\n<p>\u9ad8\u5371\u884c\u4e3a\u540e\u591a\u4e45\u68c0\u6d4b\uff1f\u9ad8\u5371\u6027\u884c\u4e3a\u4e00\u6b21\u8981\u5403\u963b\u65ad\u836f\u5417\uff1f\u53d1\u751f\u9ad8\u5371\u6027\u884c\u4e3a\u540e\u600e\u4e48\u529e\uff1f\u9ad8\u5371\u884c\u4e3a\u591a\u5c11\u5929\u540e\u53ef\u4ee5\u5f7b\u5e95\u6392\u9664\uff1f\u7b49\u7b49\u95ee\u9898\uff0c\u53ef\u4ee5\u5728\u4e92\u8054\u7f51\u533b\u9662\u514d\u8d39\u54a8\u8be2\u4e13\u4e1a\u611f\u67d3\u79d1\u533b\u5e08\u3002<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"size-full wp-image-127 aligncenter\" src=\"http:\/\/baijianyy.cn\/wp-content\/uploads\/2023\/12\/mmexport1702183130138.gif\" alt=\"\" width=\"300\" height=\"300\" \/><\/p>\n<p>\u4e0a\u9976\u5e02\u5a7a\u6e90\u53bf\u81ea\u613f\u54a8\u8be2\u68c0\u6d4b\u673a\u6784\uff1a \u5a7a\u6e90\u53bf\u76ae\u80a4\u75c5\u6027\u75c5\u9632\u6cbb\u6240<\/p>\n<p>\u5730\u5740\uff1a\u5a7a\u6e90\u53bf\u6587\u535a\u8def<\/p>\n<p>\u963b\u65ad\u836f\u4e3a\u4ec0\u4e48\u8981\u540328\u5929\uff1f\u6b64\u95ee\u9898\u8bf7\u626b\u4e0a\u9762\u7684\u7801\u5173\u6ce8\u4e92\u8054\u7f51\u533b\u9662\uff0c\u4e3a\u60a8\u89e3\u7b54<\/p>\n<p><img decoding=\"async\" loading=\"lazy\" class=\"aligncenter size-full wp-image-2469\" src=\"http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/tD3joxnhIj_small.jpg\" alt=\"\" width=\"800\" height=\"520\" srcset=\"http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/tD3joxnhIj_small.jpg 800w, http:\/\/baijianyy.cn\/wp-content\/uploads\/2024\/03\/tD3joxnhIj_small-768x499.jpg 768w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/p>\n<p>\u7f8e\u56fd\u56f4\u4ea7\u671f HIV \u4e34\u5e8a\u6307\u5357<\/p>\n<p>2024 \u5e74 1 \u6708 31 \u65e5\u66f4\u65b0\u8981\u70b9<\/p>\n<p>\u4e3b\u8981\u7684\u66f4\u65b0\u70b9\u5982\u4e0b\uff1a<\/p>\n<p>1.\u6000\u5b55\u548c\u4ea7\u540eHIV \u68c0\u6d4b\u4ee5\u53ca\u56f4\u4ea7\u671f\u548c\u4ea7\u540eHIV \u66b4\u9732\u7684\u8bc6\u522b<\/p>\n<p>\u4e13\u5bb6\u7ec4\u5efa\u8bae\uff0c\u5728\u6000\u5b55\u671f\u95f4\u3001\u5206\u5a29\u671f\u6216\u54fa\u4e73\u671f\u6000\u7591\u6025\u6027HIV\u611f\u67d3\u65f6\uff0c\u5e94\u8be5\u7ed3\u5408\u6297\u539f\/\u6297\u4f53\u514d\u75ab\u5206\u6790\u4e0e\u8840\u6d46HIV RNA\u6d4b\u5b9a\u4e00\u540c\u8fdb\u884c<\/p>\n<p>2.\u66b4\u9732\u524d\u9884\u9632(PrEP)\u53ef\u5728\u56f4\u5b55\u671f\u3001\u4ea7\u524d\u548c\u4ea7\u540e\u671f\u95f4<a href=\"http:\/\/baijianyy.cn\/?tag=%e9%a2%84%e9%98%b2hiv\" title=\"\u6d4f\u89c8\u5173\u4e8e\u201c\u9884\u9632HIV\u201d\u7684\u6587\u7ae0\" target=\"_blank\" class=\"tag_link\">\u9884\u9632HIV<\/a><\/p>\n<p>-\u9274\u4e8e\u7f3a\u4e4f\u6570\u636e\uff0c\u4e0d\u5efa\u8bae\u91c7\u7528\u95f4\u6b47\u6027\u6216\u975e\u6bcf\u65e5PrEP\u6765\u9884\u9632\u9634\u9053\u66b4\u9732\u4e8eHIV\u3002<\/p>\n<p>-\u5bf9\u4e8e\u8ba1\u5212\u505c\u6b62\u6bcf\u65e5\u53e3\u670dPrEP\u7684\u4eba\uff0c\u5efa\u8bae\u5728\u6700\u540e\u4e00\u6b21\u63a5\u89e6HIV\u540e\u6301\u7eed\u4f7f\u75287\u81f328\u5929\u3002\u8be5\u65f6\u95f4\u8303\u56f4\u4e0e\u66b4\u9732\u540e\u9884\u9632\u7684\u5efa\u8bae\u4e00\u81f4\u3002<\/p>\n<p>-\u5bf9\u4e8e\u5728\u63a5\u53d7PrEP\u671f\u95f4\u6000\u5b55\u7684\u4eba\uff0c\u5305\u62ec\u5c1a\u672a\u6279\u51c6\u7528\u4e8e\u6000\u5b55\u671f\u95f4PrEP\u7684\u836f\u7269\uff08\u4f8b\u5982\u957f\u6548\u6ce8\u5c04\u7528\u5361\u535a\u7279\u97e6[CAB-LA]\u3001\u4e19\u915a\u66ff\u8bfa\u798f\u97e6[TAF]\uff09\uff0c\u5f3a\u70c8\u5efa\u8bae\u4e34\u5e8a\u533b\u751f\u5728\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u836f\u7269\u6ce8\u518c\u4e2d\u5fc3\u8fdb\u884c\u6ce8\u518c\u6000\u5b55\u767b\u8bb0\u5e94\u5c3d\u65e9\u8fdb\u884c\u3002<\/p>\n<p>-\u8bc4\u4f30TAF\/\u6069\u66f2\u4ed6\u6ee8(FTC)\u4f5c\u4e3a\u9634\u9053\u66b4\u9732\u4eba\u7fa4PrEP\u7684\u529f\u6548\u7814\u7a76\u5c1a\u672a\u5b8c\u6210\u3002\u56e0\u6b64\uff0c\u4e13\u5bb6\u7ec4\u4e0d\u5efa\u8bae\u5c06 TAF\/FTC\u4f5c\u4e3a\u8be5\u4eba\u7fa4\u7684PrEP\uff0c\u5305\u62ec\u6000\u5b55\u671f\u95f4\u548c\u4ea7\u540e\u3002\u6b64\u5916\uff0cTDF\/FTC\u836f\u4ee3\u52a8\u529b\u5b66\u6570\u636e\u4e0d\u80fd\u8f7b\u6613\u5916\u63a8\u81f3TAF\/FTC\u3002<\/p>\n<p>3.\u5f53\u4f34\u4fa3\u4e00\u65b9\u6216\u53cc\u65b9<a href=\"http:\/\/baijianyy.cn\/?tag=%e6%84%9f%e6%9f%93%e8%89%be%e6%bb%8b\" title=\"\u6d4f\u89c8\u5173\u4e8e\u201c\u611f\u67d3\u827e\u6ecb\u201d\u7684\u6587\u7ae0\" target=\"_blank\" class=\"tag_link\">\u611f\u67d3\u827e\u6ecb<\/a>\u75c5\u6bd2\u65f6\u7684\u751f\u80b2\u9009\u62e9<\/p>\n<p>-\u6839\u636e\u4e2a\u4eba\u98ce\u9669\u548c\u5b55\u524d\u6301\u7eed\u65f6\u95f4\uff0c\u53ef\u4ee5\u8003\u8651\u5728\u5c1d\u8bd5\u6000\u5b55\u65f6\u91cd\u65b0\u7b5b\u67e5\u751f\u6b96\u9053\u611f\u67d3\u3002<\/p>\n<p>-\u4e3a\u4e86\u9632\u6b62\u611f\u67d3<a href=\"http:\/\/baijianyy.cn\/?tag=%e8%89%be%e6%bb%8b%e7%97%85%e6%af%92\" title=\"\u6d4f\u89c8\u5173\u4e8e\u201c\u827e\u6ecb\u75c5\u6bd2\u201d\u7684\u6587\u7ae0\" target=\"_blank\" class=\"tag_link\">\u827e\u6ecb\u75c5\u6bd2<\/a>\uff0c\u4e13\u5bb6\u5c0f\u7ec4\u5efa\u8bae\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u4e0e\u6240\u6709\u6ca1\u6709\u827e\u6ecb\u75c5\u6bd2\u7684\u6027\u6d3b\u8dc3\u4eba\u7fa4\uff08\u5305\u62ec\u8bd5\u56fe\u6000\u5b55\u7684\u4eba\uff09\u8ba8\u8bbaPrEP\u3002\u5e94\u5411\u90a3\u4e9b\u9700\u8981 PrEP\u6216\u6709PrEP\u7279\u5b9a\u9002\u5e94\u75c7\u7684\u4eba\u63d0\u4f9bPrEP\u3002<\/p>\n<p>4.\u6000\u5b55\u671f\u95f4\u827e\u6ecb\u75c5\u6bd2\u7684\u521d\u6b65\u8bc4\u4f30\u548c\u6301\u7eed\u76d1\u6d4b<\/p>\n<p>-\u5df2\u8fdb\u884c\u4fee\u8ba2\uff0c\u4ee5\u6f84\u6e05CD4 T \u6dcb\u5df4\u7ec6\u80de\u8ba1\u6570\u76d1\u6d4b\u7684\u5efa\u8bae\uff0c\u4e0e\u6210\u4eba\u548c\u9752\u5c11\u5e74\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u6307\u5357\u4e2d\u7684\u6307\u5bfc\u4fdd\u6301\u4e00\u81f4\u3002<\/p>\n<p>5.\u9488\u5bf9\u8bd5\u56fe\u6000\u5b55\u7684\u827e\u6ecb\u75c5\u6bd2\u611f\u67d3\u8005\u7684\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u6cbb\u7597<\/p>\n<p>-\u5c1a\u65e0\u5173\u4e8e\u6000\u5b55\u671f\u95f4\u6ce8\u5c04\u7528\u5361\u535a\u7279\u97e6(CAB)\u548c\u5229\u5339\u97e6\u6797(RPV)\u7684\u6709\u6548\u6027\u548c\u5b89\u5168\u6027\u7684\u6570\u636e\u3002\u5bf9\u4e8e\u90a3\u4e9b\u6b63\u5728\u8003\u8651\u5728\u53d7\u5b55\u524d\u6539\u53d8\u6cbb\u7597\u65b9\u6848\u4ee5\u9632\u6b62\u80ce\u513f\u66b4\u9732\u7684\u4eba\u6765\u8bf4\uff0c\u91cd\u8981\u7684\u662f\u8981\u8ba4\u8bc6\u5230CAB\u548cRPV\u6ce8\u5c04\u5fc5\u987b\u5728\u53d7\u5b55\u524d\u81f3\u5c111\u5e74\u505c\u6b62\uff0c\u4ee5\u786e\u4fdd\u8fd9\u4e9b\u957f\u6548\u836f\u7269\u88ab\u5b8c\u5168\u6d88\u9664\u3002<\/p>\n<p>-\u5728\u63a5\u53d7\u957f\u6548\u6ce8\u5c04\u578b\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u6cbb\u7597(ART)\u4e14\u6709\u53e3\u670d\u836f\u7269\u4f9d\u4ece\u6027\u8f83\u5dee\u7684\u75c5\u53f2\u7684\u60a3\u8005\u4e2d\uff0c\u4ece\u957f\u6548\u6ce8\u5c04\u578bCAB\u548cRPV\u8f6c\u4e3a\u53e3\u670dART\u6765\u51c6\u5907\u53d7\u5b55\u53ef\u80fd\u4f1a\u589e\u52a0\u75c5\u6bd2\u53cd\u5f39\u548c\u611f\u67d3\u7684\u98ce\u9669\u548c\u975e\u6838\u82f7\u7c7b\u9006\u8f6c\u5f55\u9176\u6291\u5236\u5242\u7684\u8010\u836f\u3002\u5728\u505a\u51fa\u5173\u4e8e\u6539\u4e3a\u53e3\u670d\u7597\u6cd5\u7684\u51b3\u5b9a\u65f6\uff0c\u5e94\u91c7\u7528\u5171\u540c\u51b3\u7b56\u3002<\/p>\n<p>6.\u4ece\u672a\u63a5\u53d7\u8fc7\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u836f\u7269\u7684\u827e\u6ecb\u75c5\u6bd2\u611f\u67d3\u8005\u5b55\u5987\uff08\u672a\u63a5\u53d7\u8fc7\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u6cbb\u7597\uff09<\/p>\n<p>-\u5bf9\u4e8e\u4ece\u672a\u63a5\u53d7\u8fc7\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2(ARV)\u836f\u7269\u7684\u5b55\u5987\uff0c\u4ee5\u4e0b\u57fa\u4e8e\u591a\u66ff\u62c9\u97e6(DTG)\u7684\u65b9\u6848\u4f18\u9009\u4f5c\u4e3a\u521d\u59cbART\uff1a<\/p>\n<p>DTG +\uff08\u5bcc\u9a6c\u9178\u66ff\u8bfa\u798f\u97e6\u4e8c\u5421\u544b\u916f [TDF] \u6216 TAF\uff09+\uff08FTC \u6216\u62c9\u7c73\u592b\u5b9a [3TC]\uff09\u6216<\/p>\n<p>DTG + \u963f\u5df4\u5361\u97e6 (ABC) \u52a0 3TC\u2014\u2014\u4ec5\u9002\u7528\u4e8e HLA-B*5701 \u9634\u6027\u4e14\u65e0\u6162\u6027\u4e59\u578b\u809d\u708e\u75c5\u6bd2 (HBV) \u5408\u5e76\u611f\u67d3\u7684\u4e2a\u4f53<\/p>\n<p>-\u7136\u800c\uff0c\u5bf9\u4e8e\u6709PrEP\u66b4\u9732\u53f2\u7684\u4eba\uff0c\u7531\u4e8e\u62c5\u5fc3\u6574\u5408\u9176\u94fe\u8f6c\u79fb\u6291\u5236\u5242(INSTI)\u8010\u836f\u7a81\u53d8\uff0c\u4ee5\u4e0b\u5229\u6258\u90a3\u97e6\u589e\u5f3a\u7684\u8fbe\u82a6\u90a3\u97e6(DRV\/r)\u65b9\u6848\u662f\u521d\u59cbART\u7684\u9996\u9009\u65b9\u6848\uff1a<\/p>\n<p>DRV\/r +\uff08TDF \u6216 TAF\uff09+\uff08FTC \u6216 3TC\uff09\u6216<\/p>\n<p>DRV\/r + ABC + 3TC\u2014\u2014\u4ec5\u9002\u7528\u4e8e HLA-B*5701 \u9634\u6027\u4e14\u65e0 HBV \u5408\u5e76\u611f\u67d3\u7684\u4e2a\u4f53<\/p>\n<p>-\u5728\u5176\u4ed6\u60c5\u51b5\u4e0b\uff0c\u73b0\u5728\u5efa\u8bae\u5c06DRV\/r\u4f5c\u4e3a\u598a\u5a20\u671f\u4f7f\u7528\u7684\u66ff\u4ee3\u65b9\u6848\u800c\u4e0d\u662f\u9996\u9009\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u836f\u7269\uff1b<\/p>\n<p>7.\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u6cbb\u7597\u672a\u8fbe\u5230\u75c5\u6bd2\u6291\u5236\u6548\u679c\u7684\u5b55\u5987<\/p>\n<p>-\u8fdb\u884c\u4e86\u4fee\u8ba2\uff0c\u66f4\u65b0\u4e86\u6709\u5173\u7f3a\u4e4f\u75c5\u6bd2\u6291\u5236\u548c\u75c5\u6bd2\u5b66\u5931\u8d25\u7684\u5b9a\u4e49\u3001\u8bc4\u4f30\u548c\u7ba1\u7406\u7684\u9879\u76ee\u7b26\u53f7\u5efa\u8bae\u548c\u6587\u672c\u3002<\/p>\n<p>-\u4e13\u5bb6\u7ec4\u4e0d\u5efa\u8bae\u5728\u75c5\u6bd2\u5b66\u5931\u8d25\u7684\u6cbb\u7597\u65b9\u6848\u4e2d\u6dfb\u52a0\u5355\u4e00\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u836f\u7269\u3002\u6210\u4eba\u548c\u9752\u5c11\u5e74\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u6307\u5357\u8ba8\u8bba\u4e86\u9488\u5bf9\u672a\u5b9e\u73b0\u75c5\u6bd2\u6291\u5236\u6216\u75c5\u6bd2\u8f7d\u91cf\u53cd\u5f39\uff08\u53c2\u89c1\u75c5\u6bd2\u5b66\u5931\u8d25\uff09\u60c5\u51b5\u7684\u5177\u4f53\u6cbb\u7597\u65b9\u6848\u4fee\u6539\uff0c\u53ef\u4ee5\u7ed3\u5408\u88687\u8003\u8651.\u5b55\u5987\u548c\u8bd5\u56fe\u6000\u5b55\u7684\u975e\u5b55\u5987\u4f7f\u7528\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u836f\u7269\u3002<\/p>\n<p>\u88687.\u9488\u5bf9\u5b55\u5987\u548c\u8bd5\u56fe\u6000\u5b55\u7684\u975e\u5b55\u5987\u4f7f\u7528\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u836f\u7269\u7684\u5177\u4f53\u60c5\u51b5\u5efa\u8bae<\/p>\n<p>-\u6839\u636e\u598a\u5a20\u671f\u836f\u4ee3\u52a8\u529b\u5b66\u7684\u65b0\u6570\u636e\u548c\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u598a\u5a20\u767b\u8bb0\u5904\u7684\u6700\u65b0\u4fe1\u606f\uff0c\u6bd4\u514b\u66ff\u62c9\u97e6(BIC)\u73b0\u5728\u88ab\u63a8\u8350\u4f5c\u4e3a\u598a\u5a20\u671f\u548c\u8bd5\u56fe\u6000\u5b55\u4eba\u7fa4\u7684\u66ff\u4ee3\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u836f\u7269\uff1b\u5b83\u4e4b\u524d\u88ab\u63a8\u8350\u5728\u6000\u5b55\u671f\u95f4\u4f7f\u7528\uff0c\u4f46\u88ab\u5f52\u7c7b\u4e3a\u6570\u636e\u4e0d\u8db3\u3002\u73b0\u5728\u6570\u636e\u4ecd\u7136\u6709\u9650\uff0c\u4f46\u5c1a\u672a\u89c2\u5bdf\u5230\u5b89\u5168\u95ee\u9898\u3002<\/p>\n<p>&#8211; DRV\/r \u73b0\u5728\u88ab\u63a8\u8350\u4f5c\u4e3a\u6000\u5b55\u671f\u95f4\u548c\u8bd5\u56fe\u6000\u5b55\u7684\u4eba\u7684\u66ff\u4ee3\u65b9\u6848\uff0c\u800c\u4e0d\u662f\u9996\u9009ARV\u3002\u7136\u800c\uff0c\u5bf9\u4e8e\u6709 PrEP\u66b4\u9732\u53f2\u7684\u5b55\u5987\uff0c\u7531\u4e8e\u62c5\u5fc3INSTI\u8010\u836f\u7a81\u53d8\uff0cDRV\/r\u662f\u521d\u59cbART\u6cbb\u7597\u65b9\u6848\u7684\u9996\u9009ARV\u3002<\/p>\n<p>-\u5efa\u8bae\u5c06DRV\/r\uff0c\u800c\u4e0d\u662f\u5229\u6258\u90a3\u97e6\u589e\u5f3a\u963f\u624e\u90a3\u97e6(ATV\/r)\u4f5c\u4e3a\u975e\u598a\u5a20\u6210\u4eba\u521d\u59cbART\u7684\u9009\u62e9\u3002\u7136\u800c\uff0cDRV\/r\u9700\u8981\u5728\u6000\u5b55\u671f\u95f4\u6bcf\u5929\u7ed9\u836f\u4e24\u6b21\uff0c\u5e76\u4e14\u7ed9\u836f\u9891\u7387\u4f1a\u5f71\u54cdARV\u4f9d\u4ece\u6027\u3002\u56e0\u6b64\uff0c\u5f53\u6000\u5b55\u671f\u95f4\u9700\u8981\u4f7f\u7528\u57fa\u4e8e\u86cb\u767d\u9176\u6291\u5236\u5242\u7684\u6cbb\u7597\u65b9\u6848\u65f6\uff0c\u4e00\u4e9b\u4e13\u5bb6\u7ec4\u6210\u5458\u4f1a\u4f7f\u7528ATV\/r\u800c\u4e0d\u662fDRV\/r\u3002<\/p>\n<p>&#8211; Fostemsavir \u548cIbalizumab (IBA) \u7684\u4e13\u5bb6\u7ec4\u5efa\u8bae\u5df2\u4ece\u201c\u4e0d\u63a8\u8350\u201d\u4fee\u6539\u4e3a\u201c\u4e0d\u63a8\u8350\uff0c\u7279\u6b8a\u60c5\u51b5\u9664\u5916\u201d\uff0c\u56e0\u4e3a\u67d0\u4e9b\u5177\u6709\u590d\u6742\u6cbb\u7597\u7ecf\u9a8c\u7684\u5b55\u5987\u53ef\u80fd\u9700\u8981\u5b83\u4eec\u3002<\/p>\n<p>-\u9644\u5f55C\uff1a\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u54a8\u8be2\u6307\u5357\u5df2\u66f4\u65b0\uff0c\u7eb3\u5165\u4e86\u8868\u683c\u548c\u6587\u672c\u90e8\u5206\u7684\u66f4\u6539\uff0c\u8fd9\u4e9b\u5185\u5bb9\u6d89\u53ca\u6709\u5173\u598a\u5a20\u671f\u95f4\u4f7f\u7528\u7279\u5b9a\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u836f\u7269\u7684\u5efa\u8bae\u3002<\/p>\n<p>8.HIV-2\u611f\u67d3\u548c\u6000\u5b55<\/p>\n<p>-BIC\u88ab\u6dfb\u52a0\u5230\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u836f\u7269\u4e2d\uff0c\u63a8\u8350\u7528\u4e8e\u6cbb\u7597\u6000\u5b55\u671f\u95f4\u548c\u8bd5\u56fe\u6000\u5b55\u7684\u4eba\u7684HIV-2\u611f\u67d3\u3002<\/p>\n<p>-\u5bf9\u4e8e\u60a3\u6709\u591a\u91cd\u8010\u836f\u75c5\u6bd2\u7684\u60a3\u8005\uff0cIBA\u548cLenacapavir (LEN) \u5728\u4f53\u5916\u663e\u793a\u51fa\u6297HIV-2\u7684\u6548\u529b\uff0c\u53ef\u4ee5\u8003\u8651\u4f7f\u7528\uff1b\u9664\u7279\u6b8a\u60c5\u51b5\u5916\uff0c\u4e0d\u5efa\u8bae\u5728\u6000\u5b55\u671f\u95f4\u4f7f\u7528\u8fd9\u4e9b\u836f\u7269\u3002<\/p>\n<p>9.\u65e9\u671f\uff08\u6025\u6027\u548c\u8fd1\u671f\uff09HIV\u611f\u67d3<\/p>\n<p>-\u6839\u636e\u4e13\u5bb6\u7ec4\u5173\u4e8e\u6000\u5b55\u671f\u95f4\u4f7f\u7528BIC\u7684\u5efa\u8bae\u7684\u53d8\u5316\uff0c\u73b0\u5728\u5efa\u8baeBIC\/TAF\/FTC\u4f5c\u4e3a\u65e9\u671f\u611f\u67d3\u4e14\u6ca1\u6709\u4f7f\u7528CAB-LA\u4f5c\u4e3aPrEP\u5386\u53f2\u7684\u5b55\u5987\u7684\u66ff\u4ee3ART\u65b9\u6848\u3002<\/p>\n<p>10.\u66b4\u9732\u4e8e\u827e\u6ecb\u75c5\u6bd2\u7684\u65b0\u751f\u513f\u7684\u521d\u59cb\u4ea7\u540e\u7ba1\u7406<\/p>\n<p>-\u6dfb\u52a0\u4e86\u6709\u5173\u56f4\u4ea7\u671fHIV\u66b4\u9732\u5a74\u513f\uff08\u4f8b\u5982\u5148\u5929\u6027\u5de8\u7ec6\u80de\u75c5\u6bd2\u3001\u4e19\u578b\u809d\u708e\u75c5\u6bd2\u3001HBV\uff09\u7684\u75c5\u6bd2\u5408\u5e76\u611f\u67d3\u5efa\u8bae\u68c0\u6d4b\u7684\u4fe1\u606f\uff0c\u4ee5\u53ca\u6709\u5173\u68c0\u6d4b\u548c\u62a4\u7406\u7684\u8d44\u6e90\u94fe\u63a5\u3002<\/p>\n<p>\u603b\u7ed3\uff1a\u5fc5\u59a5\u7ef4\u5728\u4e4b\u524d\u88ab\u63a8\u8350\u5728\u6000\u5b55\u671f\u95f4\u4f7f\u7528\uff0c\u4f46\u88ab\u5f52\u7c7b\u4e3a\u6570\u636e\u4e0d\u8db3\uff0c\u6839\u636e\u8fd1\u671f\u7f8e\u56fd\u56f4\u4ea7\u671f HIV \u4e34\u5e8a\u6307\u5357\u7684\u66f4\u65b0\uff0c\u6bd4\u514b\u66ff\u62c9\u97e6(BIC)\u73b0\u5728\u88ab\u63a8\u8350\u4f5c\u4e3a\u598a\u5a20\u671f\u548c\u8bd5\u56fe\u6000\u5b55\u4eba\u7fa4\u7684\u66ff\u4ee3\u6297\u9006\u8f6c\u5f55\u75c5\u6bd2\u836f\u7269\uff0c\u8fd9\u5bf9\u4e8e\u5b55\u5987\u6765\u8bf4\u53c8\u591a\u4e86\u4e00\u79cd\u836f\u7269\u7684\u9009\u62e9\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n","protected":false},"excerpt":{"rendered":"\u827e\u6ecb\u75c5\u963b\u65ad\u836f\u54ea\u91cc\u8d2d\u4e70\uff0c\u827e\u6ecb\u75c5\u963b\u65ad\u836f\u4ef7\u683c\uff0c\u827e\u6ecb\u75c5\u963b\u65ad\u836f\u54c1\u9500\u552e\u673a\u6784\uff1f","protected":false},"author":4,"featured_media":2469,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":[],"categories":[3],"tags":[156,54,557,306,266,420],"_links":{"self":[{"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/posts\/2468"}],"collection":[{"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=2468"}],"version-history":[{"count":1,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/posts\/2468\/revisions"}],"predecessor-version":[{"id":2470,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/posts\/2468\/revisions\/2470"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=\/wp\/v2\/media\/2469"}],"wp:attachment":[{"href":"http:\/\/baijianyy.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=2468"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=2468"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/baijianyy.cn\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=2468"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}